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Herpes Simplex Virus as a Source of Thymidine Kinase for Thymidine Kinase-Deficient Mouse Cells: Suppression and Reactivation of the Viral Enzyme

Thymidine kinase (EC 2.7.1.21)-deficient mouse cells were infected with inactivated herpes simplex virus, after which “transformed” cells that produce viral thymidine kinase were isolated. Shortly after transformation, the expression of the viral enzyme could be suppressed and reactivated with high...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Davidson, Richard L., Adelstein, S. J., Oxman, Michael N.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1973
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433631/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4352962/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.7.1912
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