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Polymer-encapsulated cells genetically modified to secrete human nerve growth factor promote the survival of axotomized septal cholinergic neurons.

Effective treatments for neurodegenerative disorders are limited by our inability to alter the progression of the diseases. A number of proteins have specific neuroprotective activities in vitro; however, the delivery of these factors into the central nervous system over the long term at therapeutic...

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Main Authors: Winn, S R, Hammang, J P, Emerich, D F, Lee, A, Palmiter, R D, Baetge, E E
Formato: Artigo
Idioma:Inglês
Publicado: 1994
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC43363/
https://ncbi.nlm.nih.gov/pubmed/8134395
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