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The aged monkey basal forebrain: rescue and sprouting of axotomized basal forebrain neurons after grafts of encapsulated cells secreting human nerve growth factor.

Six Rhesus monkeys between 24 and 29 years of age received unilateral transections of the fornix. Three monkeys then received intraventricular transplants of polymer-encapsulated baby hamster kidney (BHK) fibroblasts that had been genetically modified to secrete human nerve growth factor (hNGF). The...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Kordower, J H, Winn, S R, Liu, Y T, Mufson, E J, Sladek, J R, Hammang, J P, Baetge, E E, Emerich, D F
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45133/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7971980/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.23.10898
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