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Reorganization of corticostriatal circuits in healthy G2019S LRRK2 carriers
OBJECTIVE: We investigated system-level corticostriatal changes in a human model of premotor Parkinson disease (PD), i.e., healthy carriers of the G2019S LRRK2 mutation that is associated with a markedly increased, age-dependent risk of developing PD. METHODS: We compared 37 asymptomatic LRRK2 G2019...
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| 發表在: | Neurology |
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| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Lippincott Williams & Wilkins
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4336002/ https://ncbi.nlm.nih.gov/pubmed/25540317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000001189 |
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