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Lambert-Eaton syndrome IgG inhibits transmitter release via P/Q Ca(2+) channels
OBJECTIVE: To determine whether immunoglobulin G (IgG) from patients with Lambert-Eaton myasthenic syndrome (LEMS) decreases action potential–evoked synaptic vesicle exocytosis, and whether the effect is mediated by P/Q-type voltage-gated calcium channels (VGCCs). METHODS: IgG was obtained from 4 pa...
Kaydedildi:
| Yayımlandı: | Neurology |
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| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Lippincott Williams & Wilkins
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4335987/ https://ncbi.nlm.nih.gov/pubmed/25589670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000001225 |
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