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Unexpected Challenges in Treating Multidrug-Resistant Gram-Negative Bacteria: Resistance to Ceftazidime-Avibactam in Archived Isolates of Pseudomonas aeruginosa

Pseudomonas aeruginosa is a notoriously difficult-to-treat pathogen that is a common cause of severe nosocomial infections. Investigating a collection of β-lactam-resistant P. aeruginosa clinical isolates from a decade ago, we uncovered resistance to ceftazidime-avibactam, a novel β-lactam/β-lactama...

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Bibliografiset tiedot
Julkaisussa:Antimicrob Agents Chemother
Päätekijät: Winkler, Marisa L., Papp-Wallace, Krisztina M., Hujer, Andrea M., Domitrovic, T. Nicholas, Hujer, Kristine M., Hurless, Kelly N., Tuohy, Marion, Hall, Geraldine, Bonomo, Robert A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335889/
https://ncbi.nlm.nih.gov/pubmed/25451057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04238-14
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