Reduction of CD8(+) T lymphocytes in multiple sclerosis patients treated with dimethyl fumarate

OBJECTIVE: To evaluate the influence of dimethyl fumarate (DMF, Tecfidera) treatment of multiple sclerosis (MS) on leukocyte and lymphocyte subsets. METHODS: Peripheral blood leukocyte and lymphocyte subsets, including CD3(+), CD4(+), and CD8(+) T cells; CD19(+) B cells; and CD56(+) natural killer (...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neurol Neuroimmunol Neuroinflamm
Prif Awduron: Spencer, Collin M., Crabtree-Hartman, Elizabeth C., Lehmann-Horn, Klaus, Cree, Bruce A.C., Zamvil, Scott S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Lippincott Williams & Wilkins 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335821/
https://ncbi.nlm.nih.gov/pubmed/25738172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000076
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