A rare human syndrome provides genetic evidence that WNT signaling is required for reprogramming of fibroblasts to induced pluripotent stem cells

WNT signaling promotes the reprogramming of somatic cells to an induced pluripotent state. We provide genetic evidence that WNT signaling is a requisite step during the induction of pluripotency. Fibroblasts from individuals with Focal Dermal Hypoplasia (FDH), a rare genetic syndrome caused by mutat...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Cell Rep
Κύριοι συγγραφείς: Ross, Jason, Busch, Julia, Mintz, Ellen, Ng, Damian, Stanley, Alexandra, Brafman, David, Sutton, V. Reid, Van den Veyver, Ignatia, Willert, Karl
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2014
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335800/
https://ncbi.nlm.nih.gov/pubmed/25464842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.10.049
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