The effect of immunization schedule with the malaria vaccine candidate RTS,S/AS01(E) on protective efficacy and anti-circumsporozoite protein antibody avidity in African infants

BACKGROUND: The malaria vaccine RTS,S induces antibodies against the Plasmodium falciparum circumsporozoite protein (CSP) and the concentration of Immunoglobulin G (IgG) against the repeat region of CSP following vaccination is associated with protection from P. falciparum malaria. So far, only the...

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Dettagli Bibliografici
Pubblicato in:Malar J
Autori principali: Ajua, Anthony, Lell, Bertrand, Agnandji, Selidji Todagbe, Asante, Kwaku Poku, Owusu-Agyei, Seth, Mwangoka, Grace, Mpina, Maxmilliam, Salim, Nahya, Tanner, Marcel, Abdulla, Salim, Vekemans, Johan, Jongert, Erik, Lievens, Marc, Cambron, Pierre, Ockenhouse, Chris F, Kremsner, Peter G, Mordmüller, Benjamin
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335593/
https://ncbi.nlm.nih.gov/pubmed/25885325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-015-0605-7
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