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Combining Natural Sequence Variation with High Throughput Mutational Data to Reveal Protein Interaction Sites

Many protein interactions are conserved among organisms despite changes in the amino acid sequences that comprise their contact sites, a property that has been used to infer the location of these sites from protein homology. In an inter-species complementation experiment, a sequence present in a hom...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:PLoS Genet
Main Authors: Melamed, Daniel, Young, David L., Miller, Christina R., Fields, Stanley
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335499/
https://ncbi.nlm.nih.gov/pubmed/25671604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004918
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