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High-throughput sequencing reveals inbreeding depression in a natural population

Proxy measures of genome-wide heterozygosity based on approximately 10 microsatellites have been used to uncover heterozygosity fitness correlations (HFCs) for a wealth of important fitness traits in natural populations. However, effect sizes are typically very small and the underlying mechanisms re...

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Detalhes bibliográficos
Main Authors: Hoffman, Joseph I., Simpson, Fraser, David, Patrice, Rijks, Jolianne M., Kuiken, Thijs, Thorne, Michael A. S., Lacy, Robert C., Dasmahapatra, Kanchon K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956162/
https://ncbi.nlm.nih.gov/pubmed/24586051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318945111
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