Inhibition of nucleoporin member Nup214 expression by miR-133b perturbs mitotic timing and leads to cell death

BACKGROUND: Nucleoporins mediate nucleocytoplasmic exchange of macromolecules and several have been assigned active mitotic functions. Nucleoporins can participate in various mitotic functions like spindle assembly, kinetochore organisation and chromosome segregation- important for genome integrity....

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Bhattacharjya, Sumana, Roy, Kumar Singha, Ganguly, Abira, Sarkar, Shreya, Panda, Chinmay K, Bhattacharyya, Dibyendu, Bhattacharyya, Nitai P, Roychoudhury, Susanta
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335456/
https://ncbi.nlm.nih.gov/pubmed/25743594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0299-z
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