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GRK2 Targeted Knock-down Results in Spontaneous Hypertension, and Altered Vascular GPCR Signaling

Hypertension, elevated arterial pressure, occurs as the consequence of increased peripheral resistance. G protein-coupled receptors (GPCRs) contribute to the regulation of vasodilator and vasoconstrictor responses, and their activity is regulated by a family of GPCR kinases (GRKs). GRK2 expression i...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Tutunea-Fatan, Elena, Caetano, Fabiana A., Gros, Robert, Ferguson, Stephen S. G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335248/
https://ncbi.nlm.nih.gov/pubmed/25561731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.615658
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