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Quality Control of a Cytoplasmic Protein Complex: CHAPERONE MOTORS AND THE UBIQUITIN-PROTEASOME SYSTEM GOVERN THE FATE OF ORPHAN FATTY ACID SYNTHASE SUBUNIT Fas2 OF YEAST

For the assembly of protein complexes in the cell, the presence of stoichiometric amounts of the respective protein subunits is of utmost importance. A surplus of any of the subunits may trigger unspecific and harmful protein interactions and has to be avoided. A stoichiometric amount of subunits mu...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Scazzari, Mario, Amm, Ingo, Wolf, Dieter H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335207/
https://ncbi.nlm.nih.gov/pubmed/25564609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.596064
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