Essential Role for Endogenous siRNAs during Meiosis in Mouse Oocytes

The RNase III enzyme DICER generates both microRNAs (miRNAs) and endogenous short interfering RNAs (endo-siRNAs). Both small RNA species silence gene expression post-transcriptionally in association with the ARGONAUTE (AGO) family of proteins. In mammals, there are four AGO proteins (AGO1-4), of whi...

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Udgivet i:PLoS Genet
Main Authors: Stein, Paula, Rozhkov, Nikolay V., Li, Fan, Cárdenas, Fabián L., Davydenk, Olga, Vandivier, Lee E., Gregory, Brian D., Hannon, Gregory J., Schultz, Richard M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335007/
https://ncbi.nlm.nih.gov/pubmed/25695507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005013
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