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Determinants of targeting by endogenous and exogenous microRNAs and siRNAs

Vertebrate mRNAs are frequently targeted for post-transcriptional repression by microRNAs (miRNAs) through mechanisms involving pairing of 3′ UTR seed matches to bases at the 5′ end of miRNAs. Through analysis of expression array data following miRNA or siRNA overexpression or inhibition, we found t...

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Main Authors: Nielsen, Cydney B., Shomron, Noam, Sandberg, Rickard, Hornstein, Eran, Kitzman, Jacob, Burge, Christopher B
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040081/
https://ncbi.nlm.nih.gov/pubmed/17872505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.768207
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