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Purinergic control of inflammation and thrombosis: Role of P2X1 receptors

Inflammation shifts the hemostatic mechanisms in favor of thrombosis. Upon tissue damage or infection, a sudden increase of extracellular ATP occurs, that might contribute to the crosstalk between inflammation and thrombosis. On platelets, P2X1 receptors act to amplify platelet activation and aggreg...

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Detalles Bibliográficos
Publicado en:Comput Struct Biotechnol J
Main Authors: Oury, Cécile, Lecut, Christelle, Hego, Alexandre, Wéra, Odile, Delierneux, Céline
Formato: Artigo
Idioma:Inglês
Publicado: Research Network of Computational and Structural Biotechnology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334884/
https://ncbi.nlm.nih.gov/pubmed/25709760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2014.11.008
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