Independent Emergence of Artemisinin Resistance Mutations Among Plasmodium falciparum in Southeast Asia

Background. The emergence of artemisinin-resistant Plasmodium falciparum in Southeast Asia threatens malaria treatment efficacy. Mutations in a kelch protein encoded on P. falciparum chromosome 13 (K13) have been associated with resistance in vitro and in field samples from Cambodia. Methods. P. fal...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Takala-Harrison, Shannon, Jacob, Christopher G., Arze, Cesar, Cummings, Michael P., Silva, Joana C., Dondorp, Arjen M., Fukuda, Mark M., Hien, Tran Tinh, Mayxay, Mayfong, Noedl, Harald, Nosten, Francois, Kyaw, Myat P., Nhien, Nguyen Thanh Thuy, Imwong, Mallika, Bethell, Delia, Se, Youry, Lon, Chanthap, Tyner, Stuart D., Saunders, David L., Ariey, Frederic, Mercereau-Puijalon, Odile, Menard, Didier, Newton, Paul N., Khanthavong, Maniphone, Hongvanthong, Bouasy, Starzengruber, Peter, Fuehrer, Hans-Peter, Swoboda, Paul, Khan, Wasif A., Phyo, Aung Pyae, Nyunt, Myaing M., Nyunt, Myat H., Brown, Tyler S., Adams, Matthew, Pepin, Christopher S., Bailey, Jason, Tan, John C., Ferdig, Michael T., Clark, Taane G., Miotto, Olivo, MacInnis, Bronwyn, Kwiatkowski, Dominic P., White, Nicholas J., Ringwald, Pascal, Plowe, Christopher V.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334802/
https://ncbi.nlm.nih.gov/pubmed/25180241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu491
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