Independent Emergence of Artemisinin Resistance Mutations Among Plasmodium falciparum in Southeast Asia

Background. The emergence of artemisinin-resistant Plasmodium falciparum in Southeast Asia threatens malaria treatment efficacy. Mutations in a kelch protein encoded on P. falciparum chromosome 13 (K13) have been associated with resistance in vitro and in field samples from Cambodia. Methods. P. fal...

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Vydáno v:J Infect Dis
Hlavní autoři: Takala-Harrison, Shannon, Jacob, Christopher G., Arze, Cesar, Cummings, Michael P., Silva, Joana C., Dondorp, Arjen M., Fukuda, Mark M., Hien, Tran Tinh, Mayxay, Mayfong, Noedl, Harald, Nosten, Francois, Kyaw, Myat P., Nhien, Nguyen Thanh Thuy, Imwong, Mallika, Bethell, Delia, Se, Youry, Lon, Chanthap, Tyner, Stuart D., Saunders, David L., Ariey, Frederic, Mercereau-Puijalon, Odile, Menard, Didier, Newton, Paul N., Khanthavong, Maniphone, Hongvanthong, Bouasy, Starzengruber, Peter, Fuehrer, Hans-Peter, Swoboda, Paul, Khan, Wasif A., Phyo, Aung Pyae, Nyunt, Myaing M., Nyunt, Myat H., Brown, Tyler S., Adams, Matthew, Pepin, Christopher S., Bailey, Jason, Tan, John C., Ferdig, Michael T., Clark, Taane G., Miotto, Olivo, MacInnis, Bronwyn, Kwiatkowski, Dominic P., White, Nicholas J., Ringwald, Pascal, Plowe, Christopher V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
Major Articles and Brief Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334802/
https://ncbi.nlm.nih.gov/pubmed/25180241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu491
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