Macrophage Polarization in Pancreatic Carcinoma: Role of Heparanase Enzyme

BACKGROUND: Tumor microenvironment, and particularly tumor-associated macrophages (TAMs), represent a key contributing factor in pancreatic ductal adenocarcinoma (PDAC) pathogenesis. Here we report that heparanase (predominant enzyme degrading heparan sulfate, the main polysaccharide found at the ce...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Natl Cancer Inst
Main Authors: Hermano, Esther, Meirovitz, Amichay, Meir, Karen, Nussbaum, Gabriel, Appelbaum, Limor, Peretz, Tamar, Elkin, Michael
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334800/
https://ncbi.nlm.nih.gov/pubmed/25326645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/dju332
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