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Macrophage Polarization in Pancreatic Carcinoma: Role of Heparanase Enzyme
BACKGROUND: Tumor microenvironment, and particularly tumor-associated macrophages (TAMs), represent a key contributing factor in pancreatic ductal adenocarcinoma (PDAC) pathogenesis. Here we report that heparanase (predominant enzyme degrading heparan sulfate, the main polysaccharide found at the ce...
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| Publicado en: | J Natl Cancer Inst |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4334800/ https://ncbi.nlm.nih.gov/pubmed/25326645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/dju332 |
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