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Altered expression of the imprinted transcription factor PLAGL1 deregulates a network of genes in the human IUGR placenta

Genomic imprinting is the epigenetic process that results in monoallelic expression of genes depending on parental origin. These genes are known to be critical for placental development and fetal growth in mammals. Aberrant epigenetic profiles at imprinted loci, such as DNA methylation defects, are...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Iglesias-Platas, Isabel, Martin-Trujillo, Alex, Petazzi, Paolo, Guillaumet-Adkins, Amy, Esteller, Manel, Monk, David
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334785/
https://ncbi.nlm.nih.gov/pubmed/24993786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu347
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