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A Temperature-Sensitive Mutation Affecting 28S Ribosomal RNA Production in Mammalian Cells
We have characterized a temperature-sensitive (ts) mutant of the hamster cell line BHK 21 that appears to have a defect in the processing of ribosomal RNA precursors at 39°. Mutant ts 422E grows at a normal rate at 33°, but upon shift to 39° growth stops after about one cell doubling. The appearance...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1973
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433474/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4515626/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.4.1273 |
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