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Sec24 is a coincidence detector that simultaneously binds two signals to drive ER export

BACKGROUND: Incorporation of secretory proteins into ER-derived vesicles involves recognition of cytosolic signals by the COPII coat protein, Sec24. Additional cargo diversity is achieved through cargo receptors, which include the Erv14/Cornichon family that mediate export of transmembrane proteins...

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Detalhes bibliográficos
Publicado no:Curr Biol
Main Authors: Pagant, Silvere, Wu, Alexander, Edwards, Samuel, Diehl, Frances, Miller, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334704/
https://ncbi.nlm.nih.gov/pubmed/25619760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.11.070
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