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Sec24p and Sec16p cooperate to regulate the GTP cycle of the COPII coat
Vesicle budding from the endoplasmic reticulum (ER) employs a cycle of GTP binding and hydrolysis to regulate assembly of the COPII coat. We have identified a novel mutation (sec24-m11) in the cargo-binding subunit, Sec24p, that specifically impacts the GTP-dependent generation of vesicles in vitro....
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2012
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3280547/ https://ncbi.nlm.nih.gov/pubmed/22157747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.444 |
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