Sec24p and Sec16p cooperate to regulate the GTP cycle of the COPII coat

Vesicle budding from the endoplasmic reticulum (ER) employs a cycle of GTP binding and hydrolysis to regulate assembly of the COPII coat. We have identified a novel mutation (sec24-m11) in the cargo-binding subunit, Sec24p, that specifically impacts the GTP-dependent generation of vesicles in vitro....

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Autors principals: Kung, Leslie F, Pagant, Silvere, Futai, Eugene, D'Arcangelo, Jennifer G, Buchanan, Roy, Dittmar, John C, Reid, Robert J D, Rothstein, Rodney, Hamamoto, Susan, Snapp, Erik L, Schekman, Randy, Miller, Elizabeth A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280547/
https://ncbi.nlm.nih.gov/pubmed/22157747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.444
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