The Interplay between Cyclic AMP, MAPK, and NF-κB Pathways in Response to Proinflammatory Signals in Microglia

Cyclic AMP is an important intracellular regulator of microglial cell homeostasis and its negative perturbation through proinflammatory signaling results in microglial cell activation. Though cytokines, TNF-α and IL-1β, decrease intracellular cyclic AMP, the mechanism by which this occurs is poorly...

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Dettagli Bibliografici
Pubblicato in:Biomed Res Int
Autori principali: Ghosh, Mousumi, Aguirre, Vladimir, Wai, Khine, Felfly, Hady, Dietrich, W. Dalton, Pearse, Damien D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2015
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334621/
https://ncbi.nlm.nih.gov/pubmed/25722974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/308461
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