The Interplay between Cyclic AMP, MAPK, and NF-κB Pathways in Response to Proinflammatory Signals in Microglia

Cyclic AMP is an important intracellular regulator of microglial cell homeostasis and its negative perturbation through proinflammatory signaling results in microglial cell activation. Though cytokines, TNF-α and IL-1β, decrease intracellular cyclic AMP, the mechanism by which this occurs is poorly...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Ghosh, Mousumi, Aguirre, Vladimir, Wai, Khine, Felfly, Hady, Dietrich, W. Dalton, Pearse, Damien D.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334621/
https://ncbi.nlm.nih.gov/pubmed/25722974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/308461
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