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Inhibition of Cellular Protein Synthesis by Double-Stranded RNA: Inactivation of an Initiation Factor

Inhibition of protein synthesis in rabbit reticulocyte lysates by double-stranded RNA is caused by the inactivation of IF-3, an initiation factor required for the recycling of ribosomes and for their binding to messenger RNA. The evidence for this is that (i) the inhibition can be overcome by additi...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Kaempfer, Raymond, Kaufman, Jennifer
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1973
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433462/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4197930/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.4.1222
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