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Directed evolution of the substrate specificity of dialkylglycine decarboxylase
Dialkylglycine decarboxylase (DGD) is an unusual pyridoxal phosphate dependent enzyme that catalyzes decarboxylation in the first and transamination in the second half-reaction of its ping-pong catalytic cycle. Directed evolution was employed to alter the substrate specificity of DGD from 2-aminoiso...
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| Vydáno v: | Biochim Biophys Acta |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4334570/ https://ncbi.nlm.nih.gov/pubmed/25500286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2014.12.003 |
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