CD8 T Cell Response Maturation Defined by Anentropic Specificity and Repertoire Depth Correlates with SIVΔnef-induced Protection

The live attenuated simian immunodeficiency virus (LASIV) vaccine SIVΔnef is one of the most effective vaccines in inducing protection against wild-type lentiviral challenge, yet little is known about the mechanisms underlying its remarkable protective efficacy. Here, we exploit deep sequencing tech...

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Bibliografiske detaljer
Udgivet i:PLoS Pathog
Main Authors: Adnan, Sama, Colantonio, Arnaud D., Yu, Yi, Gillis, Jacqueline, Wong, Fay E., Becker, Ericka A., Piatak, Michael, Reeves, R. Keith, Lifson, Jeffrey D., O’Connor, Shelby L., Johnson, R. Paul
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334552/
https://ncbi.nlm.nih.gov/pubmed/25688559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004633
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