Persistent Low-Level Replication of SIVΔnef Drives Maturation of Antibody and CD8 T Cell Responses to Induce Protective Immunity against Vaginal SIV Infection

Defining the correlates of immune protection conferred by SIVΔnef, the most effective vaccine against SIV challenge, could enable the design of a protective vaccine against HIV infection. Here we provide a comprehensive assessment of immune responses that protect against SIV infection through detail...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS Pathog
Egile Nagusiak: Adnan, Sama, Reeves, R. Keith, Gillis, Jacqueline, Wong, Fay E., Yu, Yi, Camp, Jeremy V., Li, Qingsheng, Connole, Michelle, Li, Yuan, Piatak, Michael, Lifson, Jeffrey D., Li, Wenjun, Keele, Brandon F., Kozlowski, Pamela A., Desrosiers, Ronald C., Haase, Ashley T., Johnson, R. Paul
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2016
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5189958/
https://ncbi.nlm.nih.gov/pubmed/27959961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006104
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