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Tribendimidine: Mode of Action and nAChR Subtype Selectivity in Ascaris and Oesophagostomum

The cholinergic class of anthelmintic drugs is used for the control of parasitic nematodes. One of this class of drugs, tribendimidine (a symmetrical diamidine derivative, of amidantel), was developed in China for use in humans in the mid-1980s. It has a broader-spectrum anthelmintic action against...

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Publicat a:PLoS Negl Trop Dis
Autors principals: Robertson, Alan P., Puttachary, Sreekanth, Buxton, Samuel K., Martin, Richard J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334517/
https://ncbi.nlm.nih.gov/pubmed/25679515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003495
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