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Tribendimidine: Mode of Action and nAChR Subtype Selectivity in Ascaris and Oesophagostomum

The cholinergic class of anthelmintic drugs is used for the control of parasitic nematodes. One of this class of drugs, tribendimidine (a symmetrical diamidine derivative, of amidantel), was developed in China for use in humans in the mid-1980s. It has a broader-spectrum anthelmintic action against...

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Détails bibliographiques
Publié dans:PLoS Negl Trop Dis
Auteurs principaux: Robertson, Alan P., Puttachary, Sreekanth, Buxton, Samuel K., Martin, Richard J.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334517/
https://ncbi.nlm.nih.gov/pubmed/25679515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003495
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