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Tribendimidine: Mode of Action and nAChR Subtype Selectivity in Ascaris and Oesophagostomum

The cholinergic class of anthelmintic drugs is used for the control of parasitic nematodes. One of this class of drugs, tribendimidine (a symmetrical diamidine derivative, of amidantel), was developed in China for use in humans in the mid-1980s. It has a broader-spectrum anthelmintic action against...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Robertson, Alan P., Puttachary, Sreekanth, Buxton, Samuel K., Martin, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334517/
https://ncbi.nlm.nih.gov/pubmed/25679515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003495
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