Secretion of human hepatitis B virus is inhibited by the imino sugar N-butyldeoxynojirimycin.

The imino sugar N-butyldeoxynojirimycin (NBDNJ) is a potent inhibitor of the oligosaccharide-trimming enzyme alpha-glucosidase I. Hepatitis B virus (HBV) contains three surface proteins (HBs proteins) of different sizes that are singly or doubly N-glycosylated and are essential for the formation of...

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Hlavní autoři: Block, T M, Lu, X, Platt, F M, Foster, G R, Gerlich, W H, Blumberg, B S, Dwek, R A
Médium: Artigo
Jazyk:Inglês
Vydáno: 1994
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC43345/
https://ncbi.nlm.nih.gov/pubmed/8134380
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