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Secretion of human hepatitis B virus is inhibited by the imino sugar N-butyldeoxynojirimycin.

The imino sugar N-butyldeoxynojirimycin (NBDNJ) is a potent inhibitor of the oligosaccharide-trimming enzyme alpha-glucosidase I. Hepatitis B virus (HBV) contains three surface proteins (HBs proteins) of different sizes that are singly or doubly N-glycosylated and are essential for the formation of...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Block, T M, Lu, X, Platt, F M, Foster, G R, Gerlich, W H, Blumberg, B S, Dwek, R A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43345/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8134380/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.6.2235
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