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Inhibition of protein kinase C enhances angiogenesis induced by platelet-derived growth factor C in hyperglycemic endothelial cells

BACKGROUND: Diabetes is a risk factor for the development of cardiovascular diseases with impaired angiogenesis. We have previously shown that platelet-derived growth factor C (PDGF-C) and its receptor, PDGF receptor α (PDGFR-α) were downregulated in ischemic limbs of diabetic mice, although the und...

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Detalhes bibliográficos
Publicado no:Cardiovasc Diabetol
Main Authors: Moriya, Junji, Ferrara, Napoleone
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334399/
https://ncbi.nlm.nih.gov/pubmed/25849290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-015-0180-9
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