Platelet-Derived Growth Factor-B Enhances Glioma Angiogenesis by Stimulating Vascular Endothelial Growth Factor Expression in Tumor Endothelia and by Promoting Pericyte Recruitment

Platelet-derived growth factor (PDGF)-B and its receptor (PDGF-R) β are overexpressed in human gliomas and responsible for recruiting peri-endothelial cells to vessels. To establish the role of PDGF-B in glioma angiogenesis, we overexpressed PDGF-B in U87MG glioma cells. Although PDGF-B stimulated t...

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Detalhes bibliográficos
Main Authors: Guo, Ping, Hu, Bo, Gu, Weisong, Xu, Li, Wang, Degui, Huang, Hui-Jen Su, Cavenee, Webster K., Cheng, Shi-Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2003
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851242/
https://ncbi.nlm.nih.gov/pubmed/12651601
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