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Improving intranasal delivery of neurological nanomedicine to the olfactory region using magnetophoretic guidance of microsphere carriers

BACKGROUND: Although direct nose-to-brain drug delivery has multiple advantages, its application is limited by the extremely low delivery efficiency (<1%) to the olfactory region where drugs can enter the brain. It is crucial to developing new methods that can deliver drug particles more effectiv...

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Библиографические подробности
Опубликовано в: :Int J Nanomedicine
Главные авторы: Xi, Jinxiang, Zhang, Ze, Si, Xiuhua A
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334328/
https://ncbi.nlm.nih.gov/pubmed/25709443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S77520
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