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Modeling and Simulations of Olfactory Drug Delivery with Passive and Active Controls of Nasally Inhaled Pharmaceutical Aerosols

There are many advantages of direct nose-to-brain drug delivery in the treatment of neurological disorders. However, its application is limited by the extremely low delivery efficiency (< 1%) to the olfactory mucosa that directly connects the brain. It is crucial to develop novel techniques to de...

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Podrobná bibliografie
Vydáno v:J Vis Exp
Hlavní autoři: Si, Xiuhua A., Xi, Jinxiang
Médium: Artigo
Jazyk:Inglês
Vydáno: MyJove Corporation 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927714/
https://ncbi.nlm.nih.gov/pubmed/27285852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53902
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