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Protein Hal: Partial Deletion of a “γ” Immunoglobulin Gene(s) and Apparent Reinitiation at an Internal AUG Codon

Protein Hal is a human γ4 heavy-chain disease protein whose molecular weight is reduced from 55,000 to 25,000 in 6 M guanidine due to the lack of disulfide bonds between heavy chains. Studies of aminoacid sequence indicate that it contains a gap of about 240 residues, starting 10 residues from the N...

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Bibliographic Details
Main Authors: Frangione, Blas, Lee, Loretta, Haber, Edgar, Bloch, Kurt J.
Format: Artigo
Language:Inglês
Published: 1973
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC433428/
https://ncbi.nlm.nih.gov/pubmed/4577790
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