A Rolling Circle Replication Mechanism Produces Multimeric Lariats of Mitochondrial DNA in Caenorhabditis elegans

Mitochondrial DNA (mtDNA) encodes respiratory complex subunits essential to almost all eukaryotes; hence respiratory competence requires faithful duplication of this molecule. However, the mechanism(s) of its synthesis remain hotly debated. Here we have developed Caenorhabditis elegans as a convenie...

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Publicado en:PLoS Genet
Autores principales: Lewis, Samantha C., Joers, Priit, Willcox, Smaranda, Griffith, Jack D., Jacobs, Howard T., Hyman, Bradley C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334201/
https://ncbi.nlm.nih.gov/pubmed/25693201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004985
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