The C-Type Lectin Receptor CLECSF8/CLEC4D Is a Key Component of Anti-Mycobacterial Immunity

The interaction of microbes with pattern recognition receptors (PRRs) is essential for protective immunity. While many PRRs that recognize mycobacteria have been identified, none is essentially required for host defense in vivo. Here, we have identified the C-type lectin receptor CLECSF8 (CLEC4D, MC...

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Publicado en:Cell Host Microbe
Main Authors: Wilson, Gillian J., Marakalala, Mohlopheni J., Hoving, Jennifer C., van Laarhoven, Arjan, Drummond, Rebecca A., Kerscher, Bernhard, Keeton, Roanne, van de Vosse, Esther, Ottenhoff, Tom H.M., Plantinga, Theo S., Alisjahbana, Bachti, Govender, Dhirendra, Besra, Gurdyal S., Netea, Mihai G., Reid, Delyth M., Willment, Janet A., Jacobs, Muazzam, Yamasaki, Sho, van Crevel, Reinout, Brown, Gordon D.
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2015
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Short Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334100/
https://ncbi.nlm.nih.gov/pubmed/25674984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.01.004
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