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xCT, not just an amino-acid transporter: a multi-functional regulator of microbial infection and associated diseases
Expression of xCT, a component of the x(c)(–) amino-acid transporter, is essential for the uptake of cystine required for intracellular glutathione (GSH) synthesis and maintenance of the intracellular redox balance. Therefore, xCT plays an important role not only in the survival of somatic and immun...
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| Publié dans: | Front Microbiol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4333839/ https://ncbi.nlm.nih.gov/pubmed/25745420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2015.00120 |
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