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xCT, not just an amino-acid transporter: a multi-functional regulator of microbial infection and associated diseases

Expression of xCT, a component of the x(c)(–) amino-acid transporter, is essential for the uptake of cystine required for intracellular glutathione (GSH) synthesis and maintenance of the intracellular redox balance. Therefore, xCT plays an important role not only in the survival of somatic and immun...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Dai, Lu, Noverr, Mairi C., Parsons, Chris, Kaleeba, Johnan A. R., Qin, Zhiqiang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333839/
https://ncbi.nlm.nih.gov/pubmed/25745420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2015.00120
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