Dendritic cells induce Th2-mediated airway inflammatory responses to house dust mite via DNA-dependent protein kinase

DNA-dependent protein kinase (DNA-PK) mediates double stranded DNA break repair, V(D)J recombination, and immunoglobulin class switch recombination, as well as innate immune and pro-inflammatory responses. However, there is limited information regarding the role of DNA-PK in adaptive immunity mediat...

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Pubblicato in:Nat Commun
Autori principali: Mishra, Amarjit, Brown, Alexandra L., Yao, Xianglan, Yang, Shutong, Park, Sung-Jun, Liu, Chengyu, Dagur, Pradeep K., McCoy, J. Philip, Keeran, Karen J., Nugent, Gayle Z., Jeffries, Kenneth R., Qu, Xuan, Yu, Zu-Xi, Levine, Stewart J., Chung, Jay H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333735/
https://ncbi.nlm.nih.gov/pubmed/25692509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7224
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