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Mechanism of Ca(2+)-triggered ESCRT assembly and regulation of cell membrane repair

In muscle and other mechanically active tissue, cell membranes are constantly injured and their repair depends on the injury induced increase in cytosolic calcium. Here we show that injury-triggered Ca(2+) increase results in assembly of ESCRTIII and accessory proteins at the site of repair. This pr...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Scheffer, Luana L., Sreetama, Sen Chandra, Sharma, Nimisha, Medikayala, Sushma, Brown, Kristy J., Defour, Aurelia, Jaiswal, Jyoti K.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333728/
https://ncbi.nlm.nih.gov/pubmed/25534348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6646
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