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Mechanism of Ca(2+)-triggered ESCRT assembly and regulation of cell membrane repair

In muscle and other mechanically active tissue, cell membranes are constantly injured and their repair depends on the injury induced increase in cytosolic calcium. Here we show that injury-triggered Ca(2+) increase results in assembly of ESCRTIII and accessory proteins at the site of repair. This pr...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Scheffer, Luana L., Sreetama, Sen Chandra, Sharma, Nimisha, Medikayala, Sushma, Brown, Kristy J., Defour, Aurelia, Jaiswal, Jyoti K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333728/
https://ncbi.nlm.nih.gov/pubmed/25534348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6646
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