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Site-Specific Promoter Caging Enables Optochemical Gene Activation in Cells and Animals

[Image: see text] In cell and molecular biology, double-stranded circular DNA constructs, known as plasmids, are extensively used to express a gene of interest. These gene expression systems rely on a specific promoter region to drive the transcription of genes either constitutively (i.e., in a cont...

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Détails bibliographiques
Publié dans:J Am Chem Soc
Auteurs principaux: Hemphill, James, Govan, Jeane, Uprety, Rajendra, Tsang, Michael, Deiters, Alexander
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2014
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333597/
https://ncbi.nlm.nih.gov/pubmed/24802207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja500327g
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