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Concerted, Rapid, Quantitative, and Site-Specific Dual Labeling of Proteins

[Image: see text] Rapid, one-pot, concerted, site-specific labeling of proteins at genetically encoded unnatural amino acids with distinct small molecules at physiological pH, temperature, and pressure is an important challenge. Current approaches require sequential labeling, low pH, and typically d...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Sachdeva, Amit, Wang, Kaihang, Elliott, Thomas, Chin, Jason W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333588/
https://ncbi.nlm.nih.gov/pubmed/24857040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4129789
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