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Inhibition of 5-Oxoprolinase by 2-Imidazolidone-4-Carboxylic Acid

L-2-Imidazolidone-4-carboxylic acid is an effective competitive inhibitor of the reaction catalyzed by 5-oxoprolinase, in which 5-oxo-L-proline (L-pyroglutamic acid, L-2-pyrrolidone-5-carboxylic acid, L-5-oxopyrrolidine-2-carboxylic acid) is converted to L-glutamate, with concomitant cleavage of ATP...

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書目詳細資料
發表在:Proc Natl Acad Sci U S A
Main Authors: Van Der Werf, Paul, Stephani, Ralph A., Orlowski, Marian, Meister, Alton
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 1973
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433352/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4514988/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.3.759
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