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Inhibition of 5-Oxoprolinase by 2-Imidazolidone-4-Carboxylic Acid
L-2-Imidazolidone-4-carboxylic acid is an effective competitive inhibitor of the reaction catalyzed by 5-oxoprolinase, in which 5-oxo-L-proline (L-pyroglutamic acid, L-2-pyrrolidone-5-carboxylic acid, L-5-oxopyrrolidine-2-carboxylic acid) is converted to L-glutamate, with concomitant cleavage of ATP...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1973
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433352/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4514988/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.3.759 |
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