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Inhibition of 5-Oxoprolinase by 2-Imidazolidone-4-Carboxylic Acid

L-2-Imidazolidone-4-carboxylic acid is an effective competitive inhibitor of the reaction catalyzed by 5-oxoprolinase, in which 5-oxo-L-proline (L-pyroglutamic acid, L-2-pyrrolidone-5-carboxylic acid, L-5-oxopyrrolidine-2-carboxylic acid) is converted to L-glutamate, with concomitant cleavage of ATP...

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Detalhes bibliográficos
Main Authors: Van Der Werf, Paul, Stephani, Ralph A., Orlowski, Marian, Meister, Alton
Formato: Artigo
Idioma:Inglês
Publicado em: 1973
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC433352/
https://ncbi.nlm.nih.gov/pubmed/4514988
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