Structural basis of DNA recognition by PCG2 reveals a novel DNA binding mode for winged helix-turn-helix domains

The MBP1 family proteins are the DNA binding subunits of MBF cell-cycle transcription factor complexes and contain an N terminal winged helix-turn-helix (wHTH) DNA binding domain (DBD). Although the DNA binding mechanism of MBP1 from Saccharomyces cerevisiae has been extensively studied, the structu...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Liu, Junfeng, Huang, Jinguang, Zhao, Yanxiang, Liu, Huaian, Wang, Dawei, Yang, Jun, Zhao, Wensheng, Taylor, Ian A., Peng, You-Liang
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2015
Materias:
Structural Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333399/
https://ncbi.nlm.nih.gov/pubmed/25550425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1351
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